https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 LncRNA LIMp27 Regulates the DNA Damage Response through p27 in p53-Defective Cancer Cells https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50273 Wed 12 Jul 2023 14:18:12 AEST ]]> Optimal Delay Time of CT Perfusion for Predicting Cerebral Parenchymal Hematoma After Intra-Arterial tPA Treatment https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43334 2, >4, >6, >8, and >10 s) with PH was examined using receiver operating characteristic (ROC) analysis and logistic regression. Results: Of 94 patients, 23 developed PH on follow-up imaging. Receiver operating characteristic analysis revealed that the greatest area under the curve for predicting PH occurred at DT > 4 s (area under the curve, 0.66). At this threshold of > 4 s, DT lesion volume ≥ 30.85 mL optimally predicted PH with 70% sensitivity and 59% specificity. DT > 4 s volume was independently predictive of PH in a multivariate logistic regression model (P < 0.05). Conclusions: DT > 4 s was the parameter most strongly associated with PH. The volume of moderate, not severe, hypo-perfusion on DT is more strongly associated and may allow better prediction of PH after intra-arterial tPA thrombolysis.]]> Thu 15 Sep 2022 15:04:25 AEST ]]> Stub1 maintains proteostasis of master transcription factors in embryonic stem cells https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53744 Thu 11 Jan 2024 12:15:03 AEDT ]]> TRIM27 cooperates with STK38L to inhibit ULK1-mediated autophagy and promote tumorigenesis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52226 Thu 05 Oct 2023 10:31:40 AEDT ]]>